ALT (SGPT), High

Patient presents for suspicion of possible Cushing's. LDDST did not support a diagnosis of Cushing’s, however the chemistry panel does have generalized increased liver values; all considered mild-mod. ALT, AST, ALKP all mildly increased. Mild thrombocytosis - likely excitement. SDMA mildly increased. BUN/Crea normal. Abdominal ultrasound was recommended.

Weight loss, diarrhea, decreased appetite, occasional weakness. Glucose checks have been consistently in the low 60s. HCT over 60%, ALT 299, AST 141, BG 61. Recheck BG 64.

Possible intestinal foreign body, lethargy, weakness. Panting on presentation. Current meds: Cerenia, Unasyn, IVF, Barium series started at 5pm. CBC and blood chemistry from 2/15 showed: WBC 22.57, Neu 18.66, HGB 11.4, PLT 128,. Na 144, ALT 440, ALP 379, GGT 12. In house u/a- USG 1.062, 2wbc/hpf, no bacteria, crystals unclassified 1-5/hpf. U/A pending.

12-year-old MN DSH with a history uncontrolled diabetes mellitus was presented for evaluation of ravenous appetite, shaking, and restlessness. Current therapy was 9 IU PZI SQ BID.  Urinalysis showed SG of 1.024 and glycosuria. CBC was within reference range. Abnormalities on serum biochemistry were hyperglycemia, elevated ALT and ALP activity, and hypokalemia. T4 was within reference range.

A 10-year-old FS Australian Shepherd was presented for evaluation of acute hematemesis, vomiting, diarrhea, and lethargy.  Abnormalities on physical examination were lateral recumbence, dehydration, and pyrexia (106.8).  Blood work showed thrombocytopenia and elevated ALT (655) activity. On survey radiographs possible mass in mid abdomen and hepatomegaly was evident.

A 1-year-old, FS, Australian Shepherd mixed breed canine was presented for acute onset of collapse/dizziness. This was the first episode that the patient ever had; patient was BAR prior. Hepatomegaly was seen on radiographs. Blood chemistry showed an elevated ALT, CBC/UA were WNL. 4DX heartworm test was positive, Lepto test was negative.

The patient is a 14 month old M Miniature Australian Shepherd dog who presented with an acute case of vomiting, lethargy and ataxia.  The owner was unaware of any exposure to toxins or ingestion of obstructive material. Physical exam: 10% dehydrated; mm pink but tacky; abdomen tender on palpation; weight wnl. CBC/Chem: WBC 21,120, decreased cholesterol and protein; elevated CK, ALKP, ALT, BUN and ammonia. Lepto negative.

The patient was presented for vomiting 3-4 days prior. Was recently gagging, not urinating often despite normal drinking. The patient had a decreased appetite or was not eating at all and having innappropriate defecation in the house. Blood chemistry showed liver enzyme elevation and low BUN. Bile Acids test results were high at 464.6 umol/L. An abdominal ultrasound was recommended to rule out PSS, liver disease. possible infection- Lepto? (patient from Ontario, Canada), toxin, glomerulopathy, protein starvation, chronic non-obstructive FB, Addison, glomerulopathy, other.

A 1-year-old MN DSH cat was presented for evaluation of vomiting for a duration of 3 days. The patient has a known history of frequently eating innapropriate things around the house (strings, foreign objects, etc…). The owner reported no urination or bowel movement for 2 days. No vomiting, coughing, sneezing, or diarrhea was noted. The physical examination was unremarkable. CBC and blood chemistry found an very elevated HCT of 52.7%, eosinopenia, thrombocytopenia, mild hyperglycemia, elevated BUN, elevated calcium, low albumin, and slightly elevated ALT.